New preprint: daily-life symptom dynamics in psychosis risk
Our new preprint looks at how symptoms, affect, cognition and functioning influence each other from one day to the next in people at clinical high risk (CHR) for psychosis.
We used 60 days of daily smartphone surveys (via mindLAMP) from 263 CHR individuals in the AMP SCZ consortium. Positive affect was the most influential node, shaping next-day concentration, functioning, anhedonia and positive symptoms. Baseline cognition also shaped the network dynamics.
Two take-aways: digital phenotyping pays off when we look beyond symptom scores, since functioning, cognition and positive affect are where the dynamics are. And mental health is not a snapshot; what matters is how states regulate each other over time, in real-world context.
Great work from the Cologne team, especially Hannah Hacker and Lana Kambeitz-Ilankovic, and the whole AMP SCZ consortium.