Research theme

Clinical interventions

Trials and cohorts that turn insights into better treatment for young people.

Projects

PsyLetics
PsyLetics is an innovative research project, investigating the effects of high-intensity training (HIT) in patients with schizophrenia.
Longitudinal course of cannabis-induced psychosis (CIP)
Cannabis has been identified as one of the major risk factors for developing psychosis. Recent studies show that up to 50 % of all patients with cannabis-induced psychosis (CIP) continue to develop a permanent form of a psychotic disorder.

Publications

All in this theme

Predictors of gains in social functioning after cognitive remediation in schizophrenia: Results from the multicenter ISST (Integrated Social Cognition and Social Skills Therapy) trial

Kamp, D., Riesbeck, M., Lowe, A., Weide, K., Bechdolf, A., Leopold, K., …, Muthesius, A., Kambeitz, J., …, Wölwer, W.

Schizophr Res 293, 99–108 · 2026

DOI for “Predictors of gains in social functioning after cognitive remediation in schizophrenia: Results from the multicenter ISST (Integrated Social Cognition and Social Skills Therapy) trial”

Physical exercise as a catalyst for neuroimmune balance in schizophrenia: Targeting the kynurenine pathway in the PsyLetics project

Rißmayer, M., Fischer, J., Hanssen, R., Kretschmer, A. C., Blaschke, S. J., Jelic, S., …, Kambeitz, J., …, Lichtenstein, T.

J Psychiatr Res 198, 142–150 · 2026

DOI for “Physical exercise as a catalyst for neuroimmune balance in schizophrenia: Targeting the kynurenine pathway in the PsyLetics project”

Medical Intelligence vs. Artificial Intelligence — How psychiatrists arrive at Treatment Algorithms

Vogel, D. H. V., Kambeitz, J.

Psychiatry Res 117002 · 2026

DOI for “Medical Intelligence vs. Artificial Intelligence — How psychiatrists arrive at Treatment Algorithms”

Integrated Youth Mental Health Services – niederschwellige, integrierte Angebote für junge Menschen in psychischen Krisen: Internationale Erfahrungen und die aktuelle Situation in Deutschland

Bechdolf, A., Correll, C. U., Hellenschmidt, T., Holzner, L., von Hardenberg, L., Jäckel, D., Kambeitz, J., …, Domanska, O. M.

Nervenarzt · 2025

DOI for “Integrated Youth Mental Health Services – niederschwellige, integrierte Angebote für junge Menschen in psychischen Krisen: Internationale Erfahrungen und die aktuelle Situation in Deutschland”

Enhancing early detection and treatment of psychosis in Germany: a protocol for the health economic evaluation of an artificial intelligence-guided complex intervention

Bommhardt, T., Peschl, J., Schultze-Lutter, F., Koutsouleris, N., Meisenzahl, E., Köberlein-Neu, J., CARE Study Group

BMJ Open 15, e103151 · 2025

DOI for “Enhancing early detection and treatment of psychosis in Germany: a protocol for the health economic evaluation of an artificial intelligence-guided complex intervention”