Research theme

Prediction & precision psychiatry

Machine-learning models that forecast individual outcomes in people at clinical high risk.

Projects

PRESCIENT / AMP SCZ
The PRESCIENT project, part of the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) program, focuses on predicting clinical outcomes in individuals at clinical high risk (CHR) for psychosis.
CARE Network
The CARE study, part of the CARE Network (Computer-assisted Risk Evaluation), is an innovative clinical research project aimed at early detection and prevention of psychosis.
Individualised prediction in clinical high risk
A focus of our lab is the identification of individuals that are at-risk to develop a psychiatric disorder.
Personalized cognitive training
Cognitive symptoms are a central feature of most psychiatric diseases including psychotic and affective disorders. Recent results, including work from our lab (Kambeitz-Ilankovic et al., 2019), demonstrated that cognitive training can effectively improve cognitive performance in patients with psychosis.

Publications

Unraveling suicidal ideation and behaviors in a global cohort of individuals at clinical high-risk for psychosis: Multivariable correlates and subthreshold psychotic symptoms

Damiani, S., Orlandi, M., Provenzani, U., Bortolin, E., Rovida, M., Stefanelli, R., …, Kambeitz, J., Kambeitz-Ilankovic, L., …, Penzel, N., …, Fusar-Poli, P.

Acta Psychiatr Scand · 2026

DOI for “Unraveling suicidal ideation and behaviors in a global cohort of individuals at clinical high-risk for psychosis: Multivariable correlates and subthreshold psychotic symptoms”

Predictors of gains in social functioning after cognitive remediation in schizophrenia: Results from the multicenter ISST (Integrated Social Cognition and Social Skills Therapy) trial

Kamp, D., Riesbeck, M., Lowe, A., Weide, K., Bechdolf, A., Leopold, K., …, Muthesius, A., Kambeitz, J., …, Wölwer, W.

Schizophr Res 293, 99–108 · 2026

DOI for “Predictors of gains in social functioning after cognitive remediation in schizophrenia: Results from the multicenter ISST (Integrated Social Cognition and Social Skills Therapy) trial”

Brain texture alterations predict subtle visual perceptual dysfunctions in recent onset psychosis and clinical high-risk state

Lencer, R., Sprenger, A., Meyhöfer, I., Dannlowski, U., Romer, G., Kambeitz-Ilankovic, L., Kambeitz, J., Lichtenstein, T., Rosen, M., …, PRONIA Consortium

Transl Psychiatry · 2026

DOI for “Brain texture alterations predict subtle visual perceptual dysfunctions in recent onset psychosis and clinical high-risk state”

Processing speed and verbal learning ability as predictors of assessor-rated and Ecological Momentary Assessment self-reported functioning: Findings from AMP SCZ

Pratt, D. N., Lewandowski, K. E., Hacker, H., Kambeitz-Ilankovic, L., Yassin, W., Shah, J., …, Kambeitz, J., …, Mittal, V. A.

Schizophr Bull 52 · 2026

DOI for “Processing speed and verbal learning ability as predictors of assessor-rated and Ecological Momentary Assessment self-reported functioning: Findings from AMP SCZ”

External validation and refinement of the Psychosis Polyrisk Score to detect individuals at clinical high risk for psychosis

Stefanelli, R., Oliver, D., Damiani, S., Orlandi, M., Provenzani, U., Bortolin, E., …, Kambeitz, J., Kambeitz-Ilankovic, L., …, Penzel, N., …, Fusar-Poli, P.

BMJ Ment Health 29 · 2026

DOI for “External validation and refinement of the Psychosis Polyrisk Score to detect individuals at clinical high risk for psychosis”